Main Street, West Chestnut Street, Jefferson Avenue, West Maiden Street, East Maiden Street, National Pike, Market Street, Redstone Way, West Main Street

Direction:

East/West

Western Terminus:

West Virginia-Pennsylvania state line

Eastern Terminus:

Pennsylvania-Maryland state line

Counties:

Washington, Fayette, Somerset

Signed:

Yes

US 40 is a major east/west route running most of the way across the country from Park City, Utah, to Atlantic City, New Jersey. It has a relatively short section in Pennsylvania, entering the state from the Northern Panhandle of West Virginia and runs east to Washington, Pennsylvania, where it is multiplexed with US 19 along Jefferson Avenue, West Maiden Street, and East Maiden Street through the downtown area. Then, it splits off and runs diagonally to the southeast. There is a short multiplex along with US 119 expressway where it loops around Uniontown. US 40 has a business route through Uniontown in this area. Then, US 40 crosses Chestnut Ridge in the Allegheny Mountains before reaching the state line with Maryland.

Most of US 40 in Pennsylvania is known as National Pike, reflecting the it was originally part of the National Road, the first federally funded road to the West.