Direction:
North/South
Southern Terminus:
Virginia-West Virginia state line
Northern Terminus:
West Virginia-Maryland state line
Counties:
Berkeley
Signed:
Yes

I-81 is a north/south interstate extending from Tennessee to the Canadian border in New York. It has a relatively short section in West Virginia, passing through the Eastern Panhandle as it makes its way from Virginia to Maryland, where it has an even shorter section before crossing into Pennsylvania. The one major city along I-81 in West Virginia is Martinsburg.

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