Delta Road, East Broadway, West Broadway, Main Street, South Queen Street, North Queen Street, East Market Street, West Market Street, West Philadelphia Street, East Philadelphia Street, Carlisle Avenue, Carlisle Road, Baltimore Street, York Road, High Street, College Street, B Street, Waggoners Gap Road, Veterans Way
- Direction:
- North/South
- Southern Terminus:
- Pylesville Road (MD 165) at the Maryland-Pennsylvania state line
- Northern Terminus:
- PA 75 in Port Royal
- Distance:
- 93.14 miles
- Counties:
- York, Cumberland, Perry, Juniata
- Signed:
- Yes
PA 74 is a north/south route running diagonally through the southern central area of Pennsylvania. Pylesville Road (MD 165) becomes PA 74 upon entering the state from Maryland. It runs northwest, passing through York and Carlisle and then through the mountains to end at PA 75 in Port Royal.
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