North Main Street, South Main Street, Montgomery Street, Second Street, Continental Boulevard, Mill Street, Elysburg Road, North Market Street, South Market Street, Colonial Avenue, Centre Street, West Mahoney Avenue, East Mahoney Avenue, Connerton Street, Mount Olive Boulevard, Vulcan Hill Road, Barnesville Drive, Pine Creek Drive, Mahoney Avenue, Lafayette Avenue, Hauto Highway, Stock Street

Direction:
East/West
Western Terminus:
US 15 in Montgomery
Eastern Terminus:
Market Street (US 209) and West Catawissa Street (US 209) in Nesquehoning
Distance:
79.08 miles
Counties:
Lycoming, Northumberland, Montour, Columbia, Schuylkill, Carbon
Signed:
Yes

PA 54 is an east/west route from Montgomery to Nesquehoning. It begins at US 15, a few miles south of Williamsport, and runs southeast, crossing the West Branch of the Susquehanna River and passing through interchanges with I-180 and I-80. In Danville, it crosses the Susquehanna River. It continues southeast to Ashland and then east to Nesquehoning, passing through an interchange with I-81 along the way. It ends at US 209.

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