Fallbrook Street, Dundaff Street, Salem Avenue
- Western Terminus:
- US 11 in Kingsley
- Eastern Terminus:
- Main Street (Business US 6) in Carbondale
- 20.68 miles
- Susquehanna, Lackawanna
PA 106 is an east/west route that runs diagonally from Kingsley to Carbondale. It begins at US 11 and runs southeast for about 20 miles through rural areas to end at Main Street (Business US 6).