- Southern Terminus:
- Maryland-Pennsylvania state line
- Northern Terminus:
- Pennsylvania-New York state line
- 231.82 miles
- Franklin, Cumberland, Dauphin, Lebanon, Schuylkill, Luzerne, Lackawanna, Susquehanna
I-81 is a north/south interstate extending from Tennessee to the Canadian border in New York. It enters Pennsylvania from Maryland just north of Hagerstown and runs northeast to Harrisburg and then on to Scranton. It runs north from Scranton to the New York border just south of Binghamton.
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