I-279 begins at the Penn-Lincoln Parkway (I-376/US 22/US 30) in Pittsburgh. The first section is the Fort Duquesne Bridge, which crosses the Allegheny River to the North Shore.

Photos taken May 2024.

On the other side of the bridge, the roadway splits. Bear left for exits 1B-C or right to stay on I-279. Exit 1B is for the North Shore. Exit 1C is for Ohio River Boulevard (PA 65), which provides access to the West End Bridge (US 19) south and Marshall Avenue (US 19) north.

Photos taken May 2024.

Exit 1D is for PA 28 north, Chestnut Street, and East Ohio Street.

Photo taken May 2024.