Princeton Pike, Mercer Street
- Southern Terminus:
- Princeton Avenue (US 206) and Lawrence Road (US 206) in Lawrence
- Northern Terminus:
- Nassau Street (NJ 27) in Princeton
- 9.11 miles
CR 583 is a north/south route through Lawrence and Princeton. It bypasses the section of US 206 in those two towns. The entire length is a two-lane undivided road, except for the area around its interchange with I-295, where it widens to become a four-lane divided highway.